e-ISSN 2329-0072


Published: 2016-08-09

Effect of Severity of Ankylosing Spondylitis on Psychiatric Symptoms and Quality of Life

Yasemin Ozkan, Sinem Gökçe Kütük

(Department of Physical Therapy and Rehabilitation, Dumlupinar University, School of Medicine, Kutahya, Turkey)

Med Sci Tech 2016; 57:81-87

DOI: 10.12659/MST.898837

BACKGROUND: The aim of the present study was to evaluate the relationship between ankylosing spondylitis (AS) disease severity and fatigue, quality of sleep, and psychiatric symptoms, as well as to study how this relationship interferes with all aspects of life domains and quality of life of patients.
MATERIAL AND METHODS: This study included 46 AS patients, of whom 25 had active disease and 21 had non-active disease. Erythrocyte sedimentation ratio (ESR) and C-reactive protein (CRP) were used to detect active inflammation. The Bath AS Disease Activity Index (BASDAI) and Bath AS Functional Index (BASFI) were administered to measure and evaluate disease activity. We administered the Hospital Anxiety and Depression Scale [HADS (HADS-A, HADS-D)], the Multidimensional Assessment of Fatigue (MAF) Scale, the Pittsburgh Sleep Quality Index (PSQI), and the Ankylosing Spondylitis Quality of Life Scale (ASQoL) to evaluate psychiatric symptoms, fatigue, quality of sleep, and quality of life.
RESULTS: The mean age of the patients with active disease was 29.8±6.5 years, 25.9±5.7 in the non-active group. The duration of disease in the active group was 54.1±30.0 months, and 21.7±25.8 months in the non-active group. The scores of the BASDAI in the 2 groups were 5.12±0.37 and 3.65±0.49. The scores of the BASFAI were 6.86±0.92 and 4.38±0.92. The scores of the HAD-A were 16.2±3.8 in the active group and 11.1±2.3 in the non-active group. The scores of the HAD-D were 16.9±3.9 in the active group and 9.5±3.0 in the non-active group. MAF scores were 38.4±6.7 and 26.7±4.8. PSQI scores were 10.9±4.6 and 4.0±0.5. ASQoL scores were 13.8±2.8 and 12.4±1.9.
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Keywords: Brief Psychiatric Rating Scale, Quality of Health Care, Spondylitis, Ankylosing

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