Figure 2 TCONS_00068220 modulates aggressive behaviors in breast cancer cells. TCONS_00068220 was overexpressed in the MCF-7 cell line and silenced in the MDA-MB-231 cell line via lentiviral vector-mediated transduction. (A) Verification of the efficiency of TCONS_00068220 overexpression or knockdown via qRT-PCR. (B) Cell proliferation was evaluated using a CCK8 assay after TCONS_00068220 overexpression or silencing. A transwell assay showed the effects of TCONS_00068220 expression alterations on cell migration (C) and invasion (D). * P<0.05 and ** P<0.01 vs control group.