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04 December 2021: Clinical Research

A Pilot Randomized Controlled Trial of Intermittent Theta Burst Stimulation as Stand-Alone Treatment for Post-Stroke Aphasia: Effects on Language and Verbal Functional Magnetic Resonance Imaging (fMRI)

Jane B. Allendorfer 1BCDEF* , Rodolphe Nenert 1BCDE , Jennifer Vannest 2ABCDE , Jerzy P. Szaflarski 13ABCDEFG

DOI: 10.12659/MSM.934818

Med Sci Monit 2021; 27:e934818

Figure 2 Assessments showing significant changes over time for the treatment groups between the 3 fMRI visits: (A) between baseline (T1) and immediately after treatment (T2); (B) between T2 and at 3-month follow-up (T3); (C) between T1 and T3. Mean ±SEM are indicated on the graphs, with the line at top part of graph indicates a significant difference between time points for Tx0, while the line at bottom part of graph indicates a significant difference between time points for Tx123. * P<0.05; ** P<0.01; *** P<0.001. Tx0 – 3 weeks sham; Tx123 – at least 1 week of iTBS; BNT – Boston Naming Test; COWAT – Controlled Oral Word Association Test; AQ – Aphasia Quotient score on the Western Aphasia Battery-Revised; Mini-CAL – mini-Communicative Activity Log; Recognition – read – number of correctly remembered words from the “read” condition of the verbal paired associates task.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750