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29 August 2022 : Database Analysis  

Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination

Jinfeng Huang1ABCDEF, Ruobing Li2EF, Jie Cheng3B*, Peilin Zhen1AB

DOI: 10.12659/MSM.937532

Med Sci Monit 2022; 28:e937532

Figure 9 Single cell RNA-seq analysis of COVID-19 patients from online database platform. (A) Eight-cell types were identified by the cell markers; cells were clustered by the tSNE method. (B) Violin plot of the integration of ITCH, TRIM21, RNF130, UBE2J1, FBXO11, and ASB16 expression across different cells. (C) Violin plot of ITCH, TRIM21, RNF130, UBE2J1, FBXO11, and ASB16 expression across different cells, respectively. (D) Scatter plots of all the cells with ITCH, TRIM21, RNF130, UBE2J1, FBXO11, and ASB16 expression. (E) Scatter plots of macrophages with ITCH, TRIM21, RNF130, UBE2J1, FBXO11, and ASB16 expression.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750