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11 March 2023: Database Analysis

Prognostic-Related Biomarkers in Pancreatic Ductal Adenocarcinoma Correlating with Immune Infiltrates Based on Proteomics

Yan-qi Kou 1ACEF* , Yu-ping Yang 1BCE* , Zhao-jie Pan 2E* , Shen-shen Du 1BC* , Wei-nan Yuan 1BC , Kun He 1E , Biao Nie 1A*

DOI: 10.12659/MSM.938785

Med Sci Monit 2023; 29:e938785

Figure 6 Kaplan-Meier survival curves according to high and low expression of PLG, COPS5, FYN, ITGB3, IRF3, and SPTA1 in immune cell subgroups in PDAC, and their diagnostic value in PDAC. (A) Kaplan-Meier survival analysis of the high and low groups of PLG expression in patients with PDAC based on the number of tumor-infiltrating B cells, CD8+ T cells, NK cells, and macrophages. (B) Kaplan-Meier survival analysis of the high and low groups of COPS5 expression in patients with PDAC based on the number of tumor-infiltrating B cells, CD8+ T cells, NK cells, and macrophages. (C) Kaplan-Meier survival analysis of the high and low groups of FYN expression in patients with PDAC based on the number of tumor-infiltrating B cells, CD8+ T cells, NK cells, and macrophages. (D) Kaplan-Meier survival analysis of the high and low groups of ITGB3 expression in patients with PDAC based on the number of tumor-infiltrating B cells, CD8+ T cells, NK cells, and macrophages. (E) Kaplan-Meier survival analysis of the high and low groups of IRF3 expression in patients with PDAC based on the number of tumor-infiltrating B cells, CD8+ T cells, NK cells, and macrophages. (F) Kaplan-Meier survival analysis of the high and low groups of SPTA1 expression in patients with PDAC based on the number of tumor-infiltrating B cells, CD8+ T cells, NK cells, and macrophages (KM plotter, 2022.08.23, https://kmplot.com/analysis/).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750