20 May 2004
Hepatitis B vaccination in preterm infants: three-year follow-up
Zofia Mitkowska, Małgorzata Klimek, Przemko Kwinta, Jacek J PietrzykMed Sci Monit 2004; 10(2): 48-52 :: ID: 11848
Abstract
Background: An optimal vaccination schedule for VLBW infants is still under debate. The aim of the study was to analyze factors influencing the efficacy of hepatitis B vaccination in VLBW infants.Material/Methods: 211 newborns of HBsAg negative mothers (mean birth weight 1234±24g and mean gestational age 29.2±0.18 weeks) were observed. The patients who were vaccinated before their transfer to the tertiary NICU (mean age: 1 day,range: 0–9) were enrolled into the group A (early vaccination, N=100), the others into the group B (delayed vaccination, N=111). In the group B vaccination was postponed on average until the 53rd day of life (range: 11–179 day). According to the schedule of vaccination two subgroups of infants were identified - receiving 3 doses (at the age of 0, 1 and 6 months, n=81) or 4 doses of vaccines (at the age of 0, 1, 2 and 12 months, n=105). After 2, 12 and 36 months from the beginning of vaccination the serum level of antiHBs was measured.Results: A positive response (?10mIU/ml) was found after 2 months in 42 (51%) and 60 (69%) newborns (p
Keywords: hepatitis B vaccine, immunogenicity, prematurity, Antibodies
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952