Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

25 June 2003

Talc powder vs doxycycline in the control of malignant pleural effusion: a prospective, randomized trial

Jarosław Kużdżał, Krzysztof Sładek, Dariusz Wąsowski, Jerzy Soja, Artur Szlubowski, Agnieszka Reifland, Marcin Zieliński, Andrzej Szczeklik

Med Sci Monit 2003; 9(6): PI54-59 :: ID: 12837

Abstract

Background:Various tubes have been advocated to deal with airway problems related to operative laryngoscopy. These include large- and small-diameter tubes localized in the supraglottic, subglottic, or transtracheal region.Material/Methods:We report our clinical experience with the use of the Benjet tube on 25 patients (23–64 years of age), American Society of Anesthesiologists physical status I and II, who underwent operative laryngoscopy. The Benjet tube was positioned within the trachea using a standard curved laryngoscope. Its proximal end was connected to a jet-ventilation system equipped with a pressure-limiting drive and airway-pressure gauge. A rigid microlaryngoscope was inserted, through which a sampling needle was introduced into the vicinity of the tracheal opening, for end-tidal carbon dioxide determination. Heart rate, non-invasive blood pressure, and hemoglobin oxygen saturation were continuously monitored.Results:The Benjet tube was found to be easy to introduce and remove and was unobtrusive in the larynx and trachea, allowing excellent surgical conditions. Cardiorespiratory parameters were stable and did not change from baseline values. End-tidal carbon dioxide values ranged between 34 and 35 mm Hg.Conclusions:We conclude that the Benjet tube is highly indicated for operative laryngoscopic procedures.Background:Malignant pleural effusion is a common problem in advanced cancers, contributing to the poor quality of life in this group of patients. The aim of the study was to assess the efficiency of talc powder and doxycycline in pleurodesis in patients with malignant pleural effusion in comparable conditions.Material/Methods:Of 52 patients screened, 33 entered the trial. They were randomized to the talc group (n=18) and the doxycycline group (n=15). Both groups were comparable with regard to age, sex and the most important variables influencing effectiveness of the procedure, i.e. primary malignancy and stage of metastatic involvement of the pleura. Efficiency of pleurodesis was prospectively assessed.Conclusions:Talc powder is superior to doxycycline in achieving pleurodesis in patients with malignant pleural effusion, in both short- and long-term observations.

Keywords: Anti-Bacterial Agents - therapeutic use, Breast Neoplasms - complications, Breast Neoplasms - parasitology, Doxycycline - therapeutic use, Lung Neoplasms - complications, Lung Neoplasms - pathology, Neoplasm Metastasis, Neoplasms, Unknown Primary - complications, Neoplasms, Unknown Primary - parasitology, Pleural Effusion, Malignant - prevention & control, Talc - therapeutic use

0 Comments

Editorial

01 December 2022 : Editorial  

Editorial: The World Health Organization (WHO) Fungal Priority Pathogens List in Response to Emerging Fungal Pathogens During the COVID-19 Pandemic

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.939088

Med Sci Monit 2022; 28:e939088

SARS-CoV-2/COVID-19

29 November 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit In Press; DOI: 10.12659/MSM.938647  

24 November 2022 : Clinical Research  

A Prospective Questionnaire-Based Study to Evaluate Factors Affecting the Decision to Receive COVID-19 Vacc...

Med Sci Monit In Press; DOI: 10.12659/MSM.938665  

01 November 2022 : Clinical Research  

Questionnaire-Based Study of 81 Patients in Poland to Evaluate the Course of Inflammatory Bowel Disease and...

Med Sci Monit 2022; 28:e938243

In Press

30 Nov 2022 : Clinical Research  

Retrospective Evaluation of Hematological and Clinical Factors Associated with 30-Day Mortality in 170 Pati...

Med Sci Monit In Press; DOI: 10.12659/MSM.938674  

29 Nov 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit In Press; DOI: 10.12659/MSM.938647  

28 Nov 2022 : Review article  

A Review of the Roles of Apelin and ELABELA Peptide Ligands in Cardiovascular Disease, Including Heart Fail...

Med Sci Monit In Press; DOI: 10.12659/MSM.938112  

25 Nov 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

Med Sci Monit In Press; DOI: 10.12659/MSM.937990  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750