Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

30 March 2007

Epidemiology of renal disease in children in the region of Southern Croatia: A 10-year review of regional renal biopsy databases

Mirna Bazina, Meri Glavina-Durdov, Mira Sćukanec-Špoljar, Antonela Bazina, Katarina Vukojević, Dragan Ljutić, Marijan Saraga

Med Sci Monit 2007; 13(4): CR172-176 :: ID: 481098

Abstract

Background:Epidemiological data on some renal diseases in children are available from world national registries of renal biopsies. However, there is no published study of biopsy-proven childhood glomerulonephritis in Croatia. This report is the first review of pathohistological data covering a pediatric population over a 10-year period in the Croatian region of Dalmatia.
Material/Methods:A retrospective study was done on all renal biopsies from 65 children under 18 years of age received by the Clinical Hospital Split between 1995 and 2005. The histopathological findings were reviewed to determine the pattern of biopsy-proven glomerulonephritis. Indications for renal biopsy and clinico-pathological correlations were studied. Data on serum creatinine concentration, 24-h proteinuria, hematuria, clinical diagnosis, pathohistological diagnosis, and post-biopsy complications were collected.
Results:The main indications for biopsy were nephrotic syndrome (41.5%), hematuria with proteinuria (23.1%), and isolated hematuria (12.3%). The most frequent renal diseases in decreasing order were mesangioproliferative glomerulonephritis (27.7%), IgA nephropathy (13.8%), and Henoch-Schönlein nephritis (10.8%). Tubulointerstitial nephritis, focal segmental glomerulosclerosis, and endoproliferative glomerulonephritis each accounted for 6.2%. Alport syndrome, fibrillary glomerulonephritis, and minimal change diseases were each found in 4.6% of cases. Other forms of glomerulonephritis were rarely found.
Conclusions:The present data represent the basis for a future Croatian Registry of Renal Biopsies and are an important contribution to the epidemiology of renal diseases in south-eastern Europe. Three cases of fibrillary glomerulonephritis in children with steroid-dependent nephrotic syndrome, not reported in other countries’ registries, were also found. The importance of ultrastructural analysis of biopsy specimens is emphasized.

Keywords: Child, Biopsy - classification, Adolescent, Child, Preschool, Croatia - epidemiology, Kidney Diseases - pathology, Tissue Banks

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

26 Feb 2024 : Clinical Research  

Predictive Value of Combined HbA1c and Neutrophil-to-Lymphocyte Ratio for Diabetic Peripheral Neuropathy in...

Med Sci Monit In Press; DOI: 10.12659/MSM.942509  

Most Viewed Current Articles

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750