Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

30 March 2007

Safety and usefulness of invasive arterial blood pressure monitoring in purpura fulminans resuscitation

Taher Khalil, Stéphane Leteurtre, Christine Fonteyne, Ahmed Sadik, Dominique Biarent, Francis Leclerc

Med Sci Monit 2007; 13(4): CR182-186 :: ID: 481100

Abstract

Background:Invasive blood pressure (BP) monitoring (IBPM) is recommended in the treatment of fluid-refractory septic shock, but has been suspected of inducing distal ischemia in children with purpura fulminans (PF). The aim of the study was to determine if IBPM increases the risk of limb and skin necrosis and alters outcome of children with PF.
Material/Methods:Children admitted with PF and suspected meningococcal sepsis to two PICUs were retrospectively studied. BP was invasively monitored in one unit (arterial catheter: AC group), but not in the second (controls). Treatment was otherwise in accordance with recent guidelines. Children from the two units were matched according to age and PRISM score value. Mortality and limb or skin necrosis rates were compared and catheter-related complications were analyzed.
Results:Among 156 children (1996–2004), 46 from each unit (median age: 25 months, median PRISM value: 19) could be matched. The mortality rate was 19.5% in the AC group and 21.7% in the control group (p=0.8). Nine children (6 survivors) in the AC group and 9 (8 survivors) of the controls had distal necroses (p=1). Fifty-three ACs were inserted in the AC-group children. Catheter-related complications were three hemorrhages or hematomas, one local thrombosis, and six transient distal ischemia; there were no major catheter-related complications. Distal necrosis incidence was not increased on limbs where catheters were inserted.
Conclusions:In this series of children with PF and suspected meningococcal sepsis, BP was monitored by arterial catheter in one unit; this did not affect limb and skin necrosis and mortality rates.

Keywords: Catheters, Indwelling - adverse effects, Blood Pressure Determination - methods, Child, Child, Preschool, Extremities - pathology, Monitoring, Physiologic - methods, Necrosis - etiology, Purpura, Schoenlein-Henoch - complications, Risk Assessment, Skin - pathology

0 Comments

Editorial

01 December 2022 : Editorial  

Editorial: The World Health Organization (WHO) Fungal Priority Pathogens List in Response to Emerging Fungal Pathogens During the COVID-19 Pandemic

Dinah V. Parums
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA

DOI: 10.12659/MSM.939088

Med Sci Monit 2022; 28:e939088

SARS-CoV-2/COVID-19

29 November 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit In Press; DOI: 10.12659/MSM.938647  

24 November 2022 : Clinical Research  

A Prospective Questionnaire-Based Study to Evaluate Factors Affecting the Decision to Receive COVID-19 Vacc...

Med Sci Monit In Press; DOI: 10.12659/MSM.938665  

01 November 2022 : Clinical Research  

Questionnaire-Based Study of 81 Patients in Poland to Evaluate the Course of Inflammatory Bowel Disease and...

Med Sci Monit 2022; 28:e938243

In Press

05 Dec 2022 : Database Analysis  

Impact of the De Ritis Ratio on the Prognosis of Patients with Stable Coronary Artery Disease Undergoing Pe...

Med Sci Monit In Press; DOI: 10.12659/MSM.937737  

02 Dec 2022 : Clinical Research  

Value of Early Laparoscopic Exploration for Primary Infertile Patients with Patent Fallopian Tubes Complica...

Med Sci Monit In Press; DOI: 10.12659/MSM.938637  

30 Nov 2022 : Clinical Research  

Retrospective Evaluation of Hematological and Clinical Factors Associated with 30-Day Mortality in 170 Pati...

Med Sci Monit In Press; DOI: 10.12659/MSM.938674  

29 Nov 2022 : Clinical Research  

Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warn...

Med Sci Monit In Press; DOI: 10.12659/MSM.938647  

Most Viewed Current Articles

13 Nov 2021 : Clinical Research  

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

30 Dec 2021 : Clinical Research  

Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...

DOI :10.12659/MSM.935379

Med Sci Monit 2021; 27:e935379

01 Nov 2020 : Review article  

Long-Term Respiratory and Neurological Sequelae of COVID-19

DOI :10.12659/MSM.928996

Med Sci Monit 2020; 26:e928996

08 Mar 2022 : Review article  

A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...

DOI :10.12659/MSM.936292

Med Sci Monit 2022; 28:e936292

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750