03 March 1997
Fine-structure of the transition from the sclera to the corneoscleral trabeculum in open-angle glaucoma
Piroska Follmann, Ildikó Süveges, László ValuMed Sci Monit 1997; 3(2): BR139-143 :: ID: 500624
Abstract
Background:The fine structure of the connective tissue constituents of the transition from the sclera to the corneoscleral trabeculum was studied with transmission electron microscopy in open-angle glaucoma.
Material/Methods: 29 cases were investigated. The age of the patients ranged between 50 and 85 years, the glaucoma has lasted from 2 to 30 years. The specimens were taken during trabeculectomy after previous local drug treatment and/or laser and surgical interventions. The normal material derived from eyes enucleated because of intraocular tumours, without intraocular pressure elevation.The specimens were investigated with transmission electron microscopy.
Results: The irregular scleral fibre system gradually arranged into bundles. The bundles were getting finer and finer, and next mixed with the tissue elements of the cornea, chiefly with those of Descemet's membrane. Then the characteristic fourlayered structure of the trabecular bundles developed. These considerable tissue changes were obviously the morphologic basis of the peculiar function of the trabecular meshwork. In the sclera essential pathologic changes could not be demonstrated during the progression of the disease. In the transitional area, however, according to the change of the tissue structure, the quantity of the pathologic alterations gradually increased. In the fully developed trabecular bundles all the pathologic alterations already known in open-angle glaucoma could be detected. This tendency to develop alterations, however, could be recognized in other types of glaucoma, too.
Conclusions: The data on the alterations in the transitional zone from the sclera to the corneoscleral trabeculum may add further information on the sequence of the development of alterations of the morphologic changes found in open-angle glaucoma. These may be similar in morphologic features to those found as age-related changes.
Keywords: Sclera, corneoscleral trabeculum, fine structure of transition, open-angle glaucoma, transmission electron microscopy
538 0
Editorial
01 May 2023 : Editorial
Editorial: Twenty Years On from Sequencing the Human Genome, Personalized/Precision Oncology Prepares to Meet the Challenges of Checkpoint Inhibitor TherapyDOI: 10.12659/MSM.940911
Med Sci Monit 2023; 29:e940911
In Press
30 May 2023 : Database Analysis
The COVID-19 Crisis and the Incidence of Alcohol-Related Deaths in PolandMed Sci Monit In Press; DOI: 10.12659/MSM.940904
30 May 2023 : Clinical Research
Analgesic Efficacy of Combined Thoracic Paravertebral Block and Erector Spinae Plane Block for Video-Assist...Med Sci Monit In Press; DOI: 10.12659/MSM.940247
30 May 2023 : Review article
A Review of the Mechanism of Action and Clinical Applications of Osmotic Dilators for Cervical Ripening in ...Med Sci Monit In Press; DOI: 10.12659/MSM.940127
28 May 2023 : Database Analysis
Scientometric and Visualized Analysis of Intravoxel Incoherent Motion Magnetic Resonance Imaging: 1988-2021Med Sci Monit In Press; DOI: 10.12659/MSM.938715
Most Viewed Current Articles
13 Nov 2021 : Clinical Research
Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...DOI :10.12659/MSM.932788
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical Research
Retrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...DOI :10.12659/MSM.935379
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review article
A Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...DOI :10.12659/MSM.936292
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952