03 March 1997
Ultrastructure of the placental barrier in samples from pregnancies complicated by fetal hypertrophy: a preliminary report
Adam Ziółkowski, Krystyna Olech, Henryk Grzybek, Andrzej Gabriel, Natalia Matysiak, Krzysztof Jasik, Maria Sozańka, Jan Łaskawiec, Sławomir Pawłowski, Zbigniew SzczurekMed Sci Monit 1997; 3(2): BR149-153 :: ID: 500627
Abstract
The present study includes assessment of morphological and ultrastructural differences in the afterbirth from pregnancies complicated by fetal hypertrophy (9 cases- a study group) as opposed to those from full-term pregnancies (10 cases - a control group). Abnormalities were evaluated macroscopically and on light and transmission electron microscopy. Macroscopic placental examination showed no evidence of focal abnormalities. Light microscopy (histopathological evaluation) of samples from hypotrophic pregnancies showed a decreased intervillous space with a simultaneous increase in the size of the villi, congestion of the villi and intervillous space. Additionally, moderate and severe fibrosis was noted. Transmission electron microscopy of the majority of samples showed oedema of the villous endothelial cells as well as exfoliation of the cells from the basal membrane and filling in of the new space by collagen fibres. Rugosity and thickening of the basal membrane was present. In severe endothelial exfoliation an increased number of lysosomes in the trophoblast cells directed towards the intervillous space. In the group of placentas from full-term pregnancies, moderate oedema was found in the endothelial cells, and in some cases mild trophoblast vacuolisation was also present.
Keywords: Placenta, placental morphology, fetal hypertrophy, ultrastructure, transmission electron microscopy
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
26 Feb 2024 : Clinical Research
Predictive Value of Combined HbA1c and Neutrophil-to-Lymphocyte Ratio for Diabetic Peripheral Neuropathy in...Med Sci Monit In Press; DOI: 10.12659/MSM.942509
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952