Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

01 July 1999

Reflex effects stimulating arterial baroreceptors and other cervical mechanoreceptors by neck suction in humans

Jacek J. Klawe, Gunther Hildebrandt, Jacek Przybylski, Małgorzata M. Tafil-Klawe

Med Sci Monit 1999; 5(4): BR609-614 :: ID: 503453

Abstract

The study evaluates the influence of carotid baroreceptors activation and the combined activation of baroreceptors and mechanoreceptors located in the larynx and upper part of the trachea, on airway resistance in humans. The selective activation of baroreceptors was induced by generating a negative pressure (-40 mmHg) for 5 s in two capsules placed bilaterally on the neck over the bifurcation of the carotid arteries. The single chamber encompassing both frontal and lateral parts of the neck was used for simultaneous activation of the baroreceptors and upper airway mechanoreceptors. The above methods were validated by measurement of intra-oesophageal pressure. 50% of the negative pressure in the single chamber was transmitted to the oesophagus, whereas the pressure changes in the single capsules were not reflected at oesophagal level. Selective stimulation of carotid baroreceptors decreased airway resistance, whereas the opposite was true when both carotid baroreceptors, and upper airway mechanoreceptors were stimulated concomitantly. As atropine abolished the above changes in the airway resistance, it is suggested that the cholinergic efferent pathway is responsible for their occurrence. We conclude that in humans reflexes originating from carotid baroreceptors and mechanoreceptors in the larynx and trachea influence the airway resistance. In case of simultaneous activation of baroreceptors and mechanoreceptors of the upper airways the later one prevails the former.

Keywords: Airway Resistance, laryngeal mechanoreceptors, tracheal mechanoreceptors, carotid baroreceptors

Add Comment 0 Comments

Editorial

01 February 2024 : Editorial  

Editorial: Global Health Concerns as Vaccine-Preventable Infections Including SARS-CoV-2 (JN.1), Influenza, Respiratory Syncytial Virus (RSV), and Measles Continue to Rise

Dinah V. Parums

DOI: 10.12659/MSM.943911

Med Sci Monit 2024; 30:e943911

0:00

In Press

19 Feb 2024 : Clinical Research  

Diagnostic Accuracy of Ileocolic Artery and Vein Diameter for Acute Appendicitis

Med Sci Monit In Press; DOI: 10.12659/MSM.943846  

0:00

23 Feb 2024 : Clinical Research  

Early Mobilization in Pediatric Critical Care: Exploring the Gap Between Theory and Practice in Saudi Arabia

Med Sci Monit In Press; DOI: 10.12659/MSM.942467  

0:00

01 Feb 2024 : Review article  

Enhancing Patient Adherence to Newly-Prescribed Medicine for Chronic Diseases: A Comprehensive Review and C...

Med Sci Monit In Press; DOI: 10.12659/MSM.942923  

10 Jan 2024 : Clinical Research  

Efficacy of Bakri Intrauterine Balloon in Managing Postpartum Hemorrhage: A Comparative Analysis of Vaginal...

Med Sci Monit In Press; DOI: 10.12659/MSM.943072  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750