26 March 2021>: Clinical Research
Developmental Patterns of Fecal Bile Acids in Healthy Neonates and Children
Jing-Jing Xiong 1ABCE , Hong-Wei Hu 1BCF , Chuan-Zhi Xu 2C , Jian-Wen Yin 3BC , Mei Liu 1B , Li-Zhi Zhang 1B , Yong Duan 4B , Yong-Kun Huang 1ABCE*DOI: 10.12659/MSM.928214
Med Sci Monit 2021; 27:e928214
Table 4 Changes of secondary FBAs in children at different ages.
Age (m or y) | Case (N) | DCA (pg/g of feces) | LCA (pg/g of feces) | UDCA (pg/g of feces) |
---|---|---|---|---|
6 m | 30 | 0.0344 [0.0146,0.0667] | 0.0262 [0.0167,0.2720] | 8.7172 [2.1052,30.0651] |
1 y | 30 | 0.0761 [0.0368,3.1575]* | 0.1157 [0.0482,1.4295] | 32.2537 [17.4224,53.6974]* |
2 y | 30 | 18.7148 [0.1404,53.2972]* | 6.8367 [0.7488,50.0448]* | 42.0231 [18.7474,60.8055]* |
3 y | 30 | 110.5023 [15.5455,230.3318]* | 100.9901 [2.1096,318.5185]* | 55.2294 [27.9412,182.4074]* |
6 y | 30 | 134.9758 [71.1080,189.3100]* | 83.1608 [43.8175,209.1294]* | 48.8465 [11.6218,123.3991]* |
* P≤0.01, compared to 6-month old; # P≤0.01, compared to 1-year old; @ P≤0.01, compared to 2-year old. |