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01 March 2021: Database Analysis

Comparison of Prognostic Value Among 4 Risk Scores in Patients with Acute Coronary Syndrome: Findings from the Improving Care for Cardiovascular Disease in China-ACS (CCC-ACS) Project

Jieleng Huang 12BCEF* , Xuebiao Wei 23CD* , Yu Wang 2BE , Mei Jiang 2BC , Yingwen Lin 2BC , Zedazhong Su 2BC , Peng Ran 2B , Yingling Zhou 2G , Jiyan Chen 2AG , Danqing Yu 12AG*

DOI: 10.12659/MSM.928863

Med Sci Monit 2021; 27:e928863

Table 3 Subgroup analysis of ROC curve comparison for in-hospital adverse events.

Comparison (A vs B)PCINon-PCI
DeathC-ACS vs ACEF75.981.15.2(1.8 to 8.7)0.00372.879.76.9(3.9 to 9.9)
C-ACS vs AGEF75.982.76.8(3.8 to 9.9)72.880.57.7(4.7 to 10.6)
C-ACS vs GRACE75.983.47.5(5.1 to 9.9)72.879.56.7(4.6 to 8.8)
ACEF vs AGEF81.182.71.6(−0.1 to 3.3)0.07279.780.50.8(−0.8 to 2.4)0.354
ACEF vs GRACE81.183.42.3(−0.7 to 5.2)0.13379.779.50.2(−2.3 to 2.6)0.883
AGEF vs GRACE82.783.40.7(−1.9 to 3.2)0.60880.579.50.9(−1.2 to 3.2)0.404
MACEsC-ACS vs ACEF70.371.20.9(−0.3 to 2.1)0.15772.874.82.0(0.7 to 3.3)0.003
C-ACS AGEF70.371.31.0(−0.3 to 2.1)0.13272.874.61.8(0.5 to 3.1)0.007
C-ACS vs GRACE70.373.43.1(2.3 to 3.9)72.876.43.6(2.6 to 4.5)< 0.001
ACEF vs AGEF71.271.30.1(−0.4 to 0.5)0.85874.874.60.2(−0.4 to 0.8)0.516
ACEF vs GRACE71.273.42.2(1.2 to 3.3)74.876.41.6(0.4 to 2.7)0.009
AGEF vs GRACE71.373.42.1(1.2 to 3.2)74.676.41.8(0.6 to 2.9)0.002
BleedingC-ACS vs ACEF57.759.11.4(−0.8 to 3.5)0.23457.258.91.7(−1.7 to 5.1)0.322
C-ACS vs AGEF57.759.21.5(−0.6 to 3.6)0.16857.260.63.4(0.1 to 6.6)0.045
C-ACS vs GRACE57.760.62.9(1.2 to 4.4) to 8.0)
ACEF vs AGEF59.159.20.1(−0.6 to 0.9)0.62858.960.61.7(0.0 to 3.3)0.048
ACEF vs GRACE59.160.61.5(−0.2 to 3.3)0.09058.962.83.9(1.1 to 6.7)0.005
AGEF vs GRACE59.260.61.4(−0.4 to 3.1)0.13560.662.82.2(−0.4 to 5.0)0.101
ROC – receiver operating characteristics; PCI – percutaneous transluminal coronary intervention; C-ACS – Canada Acute Coronary Syndrome risk score; ACEF – age, creatinine and ejection fraction risk score; AGEF – modified version of ACEF risk score; GRACE – Global Registry for Acute Coronary Events risk scores; MACE – major adverse clinical events.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750