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16 March 2021: Clinical Research

Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students

Jing Zhang 12ABCDEF , Mengyi Yang 1B , Pengfei Luan 1B , Wei Jia 1B , Qiujun Liu 1B , Zhanbing Ma 1A , Jie Dang 1A , Hong Lu 1A , Qian Ma 1B , Yanfeng Wang 1B , Chunlan Mu 1B , Zhenghao Huo 13AG*

DOI: 10.12659/MSM.930591

Med Sci Monit 2021; 27:e930591

Table 3 The difference of the digit ratios among SNP genotypes of CYP genes.

GenotypeL2D: 4DR2D: 4DDR-L
Mean±SDFPMean±SDFPMean±SDFP
 CC0.9676±0.03440.9250.3970.9634±0.03600.2820.754−0.0043±0.02752.1380.119
 TT0.9626±0.03310.9620±0.0337−0.0005±0.0271
 TC0.9652±0.03270.9605±0.0323−0.0047±0.0282
 CC0.9645±0.03360.1870.8300.9629±0.03510.7390.478−0.0016±0.02730.3010.740
 TT0.9645±0.03460.9619±0.0314−0.0026±0.0309
 TC0.9631±0.03220.9600±0.0320−0.0032±0.0269
 GG0.9636±0.03340.760.4680.9615±0.03290.8740.418−0.0021±0.02720.2950.744
 TT0.9771±0.03670.9755±0.0480−0.0016±0.0508
 TG0.9645±0.03060.9603±0.0344−0.0042±0.0275
 AA0.9661±0.03362.0970.1230.9649±0.03314.1130.017* −0.0012±0.02790.6250.535
 GG0.9587±0.03560.9553±0.0356−0.0034±0.0287
 AG0.9630±0.03180.9596±0.0326−0.0034±0.0270
 CC0.9705±0.03841.6470.1930.9629±0.03331.6770.187−0.0076±0.03180.8790.415
 TT0.9626±0.03190.9600±0.0339−0.0026±0.0273
 TC0.9659±0.03460.9647±0.0318−0.0012±0.0276
 AA0.9656±0.03482.4850.0840.9654±0.03430.8890.411−0.0001±0.02561.5270.218
 CC0.9613±0.03270.9602±0.0328−0.0012±0.0269
 AC0.9666±0.0330.9622±0.0337−0.0043±0.0287
 CC0.9637±0.03320.2590.7720.9605±0.03430.910.403−0.0032±0.02771.7860.168
 TT0.9609±0.03150.9665±0.02940.0056±0.0245
 TC0.9649±0.03300.9630±0.0314−0.0018±0.0277
 CC0.9609±0.03150.1540.8570.9665±0.02940.5420.5820.0056±0.02451.7230.179
 TT0.9640±0.03310.9609±0.0341−0.0031±0.0278
 TC0.9641±0.03320.9621±0.0320−0.0020±0.0274
*
SNP – single-nucleotide polymorphism.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750