07 December 2021>: Animal Study
Tissue-Protective Effect of Erdosteine on Multiple-Organ Injuries Induced by Fine Particulate Matter
Lei Cao 1ACDE , Fen Ping 1AG , Fengrui Zhang 1BCF* , Haixiang Gao 2CDF , Ping Li 1BCF , Xiaohui Ning 1BCF , Guohuan Cui 1DF , Zheng Ma 3BC , Xin Jiang 4CD , Suyan Li 5CD , Shuzhi Han 1ACDG*DOI: 10.12659/MSM.930909
Med Sci Monit 2021; 27:e930909
Supplementary Table 2 Comparisons of cytokine level in rat BALF of each group (n=10).
Group | IL-6 (pg/ml) | IL-1β (pg/ml) | TNF-α (pg/ml) | 8-OHdG (ng/ml) | 4-HNE (ug/ml) | PCC (nmol/mg·prot) |
---|---|---|---|---|---|---|
Blank control group | 7.547±1.59 | 26.981±7.051 | 5.79±1.01 | 1.299±0.118 | 5.742±1.169 | 12.084±3.034 |
Saline group | 7.442±1.777 | 25.938±7.114 | 4.42±1.185 | 1.381±0.23 | 6.251±1.254 | 13.974±2.285 |
PM2.5 exposure group | 13.167±2.413 | 54.497±9.317 | 23.773±4.881 | 2.657±0.387 | 9.747±1.555 | 34.387±4.33 |
Erdosteine intervention group | 10.041±1.835 | 45.718±4.594 | 9.169±1.49 | 1.709±0.23 | 7.071±1.159 | 18.205±3.833 |
F | 19.515 | 38.309 | 110.883 | 57.624 | 32.156 | 85.985 |
In the above table, equal letters indicate no statistical differences, >0.05; different letters indicate statistical differences, |