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10 December 2021: Clinical Research

Development and Validation of a Random Forest Risk Prediction Pneumothorax Model in Percutaneous Transthoracic Needle Biopsy

Hong Lin Wu 1ABCDEF , Gao Wu Yan 2ADF , Li Cheng Lei 3BC , Yong Du 4AD , Xiang Ke Niu 1DF , Tao Peng 1FG*

DOI: 10.12659/MSM.932137

Med Sci Monit 2021; 27:e932137

Table 2 Characteristics of validation data.

Risk factorsN=97P value
Pneumothorax (n=54)Non-pneumothorax (n=43)
Patients’ characteristics
 Age (years), Mean±SD63.3±11.162.1±13.10.654
 Gender(number), Male/Female31 (57.4%)/23 (42.6%)31 (72.1%)/12 (27.9%)0.135
Lesion characteristics
 Lesion size (mm), Mean±SD24.4±14.334.2±20.90.026
 Lesion depth (mm), Mean±SD6.7±10.52.6±4.60.037
 Lesion location (number), upper lobe (left lung)/lower lobe (left lung)/upper lobe (right lung)/middle lobe (right lung)/lower lobe (right lung)8 (14.8%)/9 (16.7%)/ 9 (16.7%)/8 (14.8%)/20 (37.0%)10 (23.3%)/11 (25.6%)/ 12 (27.9%)/3 (7.0%)/7 (16.3%)0.083
 Cavity inside the lesion (number), yes12 (22.2%)2 (4.7%)0.014
 Emphysema/bullae (number), yes7 (13.0%)9 (20.9%)0.294
 Pneumonitis (number), yes36 (66.7%)28 (65.1%)0.873
Procedure characteristics
 Length of the aerated lung traversed (mm), Mean±SD14.2±16.39.9±12.40.186
 Angle of pleural puncture (°), Mean±SD62.0±16.362.1±17.81.000
 Procedure time (min.), Mean±SD8.3±4.98.0±4.00.997
 Biopsy position (number), supine/prone20 (37.0%)/34 (63.0%)16 (37.2%)/27 (62.8%)0.986
 Crossing of pleural indentation (number), yes11 (20.4%)7 (16.3%)0.607
 Crossing the interlobar fissure (number), yes8 (14.8%)2 (4.7%)0.177
 Number of biopsy (number), 1/2/344 (81.5%)/9 (16.7%)/1 (1.9%)40 (93.0%)/3 (7.0%)/0 (0%)0.217

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750