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18 December 2021: Clinical Research

Age-Stratified Cut-Off Values for Serum Levels of N-Terminal ProB-Type Natriuretic Peptide and Mortality from Sepsis in Children Under Age 18 Years: A Retrospective Study from a Single Center

Yan-na Sun 1ABCE* , Chun-wang Lin 1ABCDEF** , Wen Tang 2BF* , Jiang-ping Zhang 1CF

DOI: 10.12659/MSM.933400

Med Sci Monit 2021; 27:e933400

Table 4 ROC analysis of serum NT-proBNP levels for short-term mortality prediction in septic children of different ages.

Patients with sepsis<1 year1–3 years4–6 years7–18 years
Subjects, n851395647
AUC (95% CI)0.815 (0.73–0.93)812 (0.69–0.92)0.806 (0.66–0.91)0.725 (0.62–0.91)
Sensitivity0.7860.8070.8140.847
Specificity0.9370.9150.8820.837
Optimal cut-off, ng/L5000450041003800
Positive likelihood ratio21.617.320.219.7
NT-proBNP – N-terminal fragment of proB-type natriuretic peptide; AUC – area under the ROC curve.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750