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25 November 2021: Clinical Research

Use of Monoclonal Antibodies Therapy for Treatment of Mild to Moderate COVID-19 in 4 Patients with Rheumatologic Disorders

Giovanni Franchin 1ADEF , Nikhitha Mantri 2ABDEF , Maleeha Zahid 2BEF , Haozhe Sun 2BE , Sudharsan R. Gongati 2BE , Diana M. Ronderos 2BE , Snigdha Gadireddy 2BE , Sridhar Chilimuri 2ABDEF*

DOI: 10.12659/MSM.934267

Med Sci Monit 2021; 27:e934267

Table 1 Description of each patient’s presenting symptoms, current therapy, follow-up period, and adverse events.

CaseUnderlying rheumatological diseaseCurrent MedicationsPresenting symptomsInfusion administeredAdverse events during infusionFollow-up durationAdverse events during follow-up period
1PsoriasisLevothyroxineVitamin B12IbuprofenFatigue, body aches, sore throat, ageusia and anosmiaBamlanivimabNone73 daysNone
2Systemic lupus erythematosusOmeprazoleNifedipineAmlodipineDenosumabMycophenolateCalciumVitamin DDuloxetineLosartanPioglitazoneSimvastatinMetforminPancreatic enzymesAnosmia, ageusia, fatigue, subjective fever and coughBamlanivimabNone87 daysNone
3Sjogren syndrome and Raynaud diseaseAspirinMetoprololOlmesartanVitamin EMagnesiumAnosmia, ageusia, fatigue, subjective fever and coughCasirivimab-imdevimabNone111 daysNone
4Psoriatic arthritisIxekizumabDulaglutideParoxetineAmlodipineBenazeprilMyalgia, subjective fever, cough, sore throat, and anosmiaCasirivimab-imdevimabNone45 daysNone

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750