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20 June 2022: Clinical Research

A Single-Center Retrospective Study to Compare the Efficacy and Safety of Modified FOLFIRINOX with S-1 as Adjuvant Chemotherapy in 71 Patients with Resected Pancreatic Carcinoma

Linhua Yao 1ABCEF , Chengwu Tang 2ABCEF , Wenming Feng 2ABFG , Hanbin Dai 2ABCE*

DOI: 10.12659/MSM.937136

Med Sci Monit 2022; 28:e937136

Table 2 Chemotherapy-induced adverse events.

EventmFFX groupS-1 groupP value
GradeGrade
12341234
Neutropenia1413521714510.5976
Thrombocytopenia914921715410.0372
Anemia1810101910100.6863
Fatigue164201813100.0226
Nausea/vomiting918601317200.0337
Diarrhea1015521613000.0018
Elevated creatinine level400020000.3393
Elevated ALT/AST level400010000.1388
Elevated total serum bilirubin level300010000.2672
Stomatitis644045200.2156
Hand-foot syndrome110042200.0569
Paresthesia652034400.6412
ALT – alanine aminotransferase; AST – aspartate aminotransferase.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750