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29 August 2022: Database Analysis

Transcriptome Analysis of Peripheral Blood Mononuclear Cells Response in Patients with Severe COVID-19 Reveals Crucial Genes Regulating Protein Ubiquitination

Jinfeng Huang 1ABCDEF* , Ruobing Li 2EF* , Jie Cheng 3B* , Peilin Zhen 1AB*

DOI: 10.12659/MSM.937532

Med Sci Monit 2022; 28:e937532

Table 3 Biological processes enrichment analysis of genes in cluster 1.

Protein ubiquitinationITCH, TRIM21, RNF130, FBXO11, UBE2J1, ASB160.026×100.0138×10
Negative regulation of NF-kappaB transcription factor activityITCH, TRIM210.0250.67
Protein ubiquitination involved in ubiquitin-dependent protein catabolic processITCH, ANAPC10.0530.85
Ubiquitin-dependent protein catabolic processITCH, FBXO110.0630.85

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750