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07 September 2022: Clinical Research

Measurement of Serum Levels of 5 Amino Acids and Dimethylamine Using Liquid Chromatography-Tandem Mass Spectrometry in Patients without Septic Associated Acute Kidney Injury and with Septic Associated Acute Kidney Injury Requiring Continuous Renal Replacement Therapy

Patrycja Leśnik 1ABCDEFG* , Lidia Łysenko 2ADEG , Mariusz G. Fleszar 3ABF , Paulina Fortuna 3ABF , Ewa Woźnica-Niesobska 2BCDE , Magdalena Mierzchała-Pasierb 3ABF , Jarosław Janc 1ABCDEFG

DOI: 10.12659/MSM.937784

Med Sci Monit 2022; 28:e937784

Table 4 Comparison of the level of amines and amino acids in the group with and without sepsis and septic shock.

Sepsisp-value*Septic shockp-value*
Yes (n=18)No (n=22)Yes (n=22)No (n=18)
Arg [umol/L]44.837.558.755.
Orn [umol/L]7.55.815.
ADMA [umol/L]
SDMA [umol/L]
DMA [umol/L]
Cit [umol/L]
n – number of patients; Me – median; Q1 – lower quartile; Q3 – upper quartile; Arg – L-arginine; Orn – L-Ornithine; ADMA – asymmetric dimethylarginine; SDMA – symmetric dimethylarginine; DMA – dimethylamine; Cit – L-citrulline.
* U Mann-Whitney test.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750