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14 September 2022: Clinical Research

C-Reactive Protein/Albumin Ratio at Diagnosis of Pediatric Inflammatory Bowel Disease: A Retrospective Multi-Center Study

Aleksandra Glapa-Nowak 1ABCDEF , Mariusz Szczepanik 1ABE , Aleksandra Banaszkiewicz 2BE , Jarosław Kwiecień 3BE , Anna Szaflarska-Popławska 4BE , Urszula Grzybowska-Chlebowczyk 5BE , Marcin Osiecki 6BE , Jarosław Kierkuś 6BE , Marcin Dziekiewicz 2BE , Jarosław Walkowiak 1ACDEFG*

DOI: 10.12659/MSM.937842

Med Sci Monit 2022; 28:e937842

Table 3 Significant correlations with CRP/albumin ratio at diagnosis in children with Crohn’s disease.

ParameternMedian (IQR)rhop value
Age at first immunosuppressive treatment [years]14313.1 (10.8–15.2)0.200.018
Time-to-first biological treatment [months]8612.1 (4.7–26.0)−0.37
Time-to-first surgery [months]1911.5 (0.0–29.1)0.560.012
Days of hospitalization for relapse/year1094.4 (1.4–7.2)0.260.007
Severe relapses from diagnosis/year1060.2 (0.0–0.5)0.310.001
PCDAI at diagnosis17232 (23–48)0.380.002
PCDAI at worst flare15039 (30–53)0.190.023
IQR – interquartile range; PCDAI – Pediatric Crohn’s Disease Activity Index.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750