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14 October 2022: Clinical Research

Correlation Between Trough Level of Abiraterone and Prostate-Specific Antigen (PSA) Response in Metastatic Hormone-Sensitive Prostate Cancer

Zin W. Myint 12ABCDEFG* , Jill M. Kolesar 23CDE , Joseph Robert McCorkle 2CDE , Jianrong Wu 4C , Carleton S. Ellis 23CDE , Danielle E. Otto 23CDE , Peng Wang 12ACDE

DOI: 10.12659/MSM.938091

Med Sci Monit 2022; 28:e938091

Table 6 Logistic regression between 3-month abiraterone trough level and 3-month prostate-specific antigen ≤1 ng/mL and 7-month abiraterone trough level and 7-month prostate-specific antigen ≤0.2 ng/mL.

PSANmean (tABI)aP value
3 months
 PSA ≤1614.590.25
 PSA >135.51
7 months
 PSA ≤0.2415.900.56
 PSA >0.211.5
a tABI, trough abiraterone;
PSA – prostate-specific antigen.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750