Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

25 January 2023: Clinical Research

Changes in Heparin-Binding Protein, Procalcitonin, and C-Reactive Protein Within the First 72 Hours Predict 28-Day Mortality in Patients Admitted to the Intensive Care Unit with Septic Shock

Hui Xue ABCDEFG , Feng Yu AFG*

DOI: 10.12659/MSM.938538

Med Sci Monit 2023; 29:e938538

Table 1 Baseline characteristics of survivors and non-survivors following septic shock.

CharacteristicsNon-survivors (n=64)Survivors (n=82)P value
Age (years)* 66.50 (53.00, 72.00)64.5 (53.00, 72.00)0.698
Male (n, %)34 (53.1%)45 (54.9%)0.833
Length of ICU stay (days)* 12.50 (9.00, 15.00)11.50 (8.00, 15.00)0.214
Comorbidities (n, %)
 Hypertension29 (45.3%)34 (41.5%)0.641
 Diabetes12 (18.7%)16 (19.5%)0.908
 Coronary heart disease23 (35.9%)29 (35.4%)0.943
 Cerebrovascular disease10 (15.6%)16 (19.5%)0.542
 COPD9 (14.1%)10 (12.2%)0.739
 Cirrhosis4 (6.2%)6 (7.3%)0.800
 Chronic kidney disease12 (18.7%)11 (13.4%)0.380
 Trauma6 (9.4%)9 (11.0%)0.752
Infection subclass (n, %)
 Pulmonary infection41 (64.1%)55 (67.1%)0.704
 Intra-abdominal infection18 (28.1%)21 (25.6%)0.723
 Urinary tract infection13 (20.3%)16 (19.5%)0.904
 Skin/soft tissue3 (4.7%)5 (6.1%)0.710
 Bloodstream34 (53.1%)30 (36.6%)0.046
 Other5 (7.8%)9 (11.0%)0.520
WBC (10/L)* 12.15 (7.67, 19.45)10.50 (7.30, 15.53)0.311
SOFA (mean±SD)10.70±2.9610.05±0.900.060
APACHE II (mean±SD)21.06±2.9719.77±0.920.000
* Median (interquartile range);
EICU – Emergency Intensive Care Unit; COPD – Chronic Obstructive Pulmonary Disease; WBC – white blood cell counts; SOFA – Sequential Organ Failure Assessment; APACHE II – Acute Physiology and Chronic Health Evaluation.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750