25 January 2023: Clinical Research
Changes in Heparin-Binding Protein, Procalcitonin, and C-Reactive Protein Within the First 72 Hours Predict 28-Day Mortality in Patients Admitted to the Intensive Care Unit with Septic Shock
Hui Xue ABCDEFG , Feng Yu AFG*DOI: 10.12659/MSM.938538
Med Sci Monit 2023; 29:e938538
Table 2 Evolution in biomarkers in patients with septic shock.
| Variables | Non-survivors (n=64) | Survivors (n=82) | P value |
|---|---|---|---|
| HBP0 | 122.25 (43.68, 189.62) | 105.55 (30.93, 168.87) | 0.301 |
| HBP1 | 139.15 (85.00, 208.27) | 67.85 (23.90, 141.85) | 0.000 |
| PCT0 | 34.00 (1.38, 70.25) | 13.35 (1.92, 35.84) | 0.000 |
| PCT1 | 62.15 (4.91, 88.30) | 12.51 (0.86, 29.22) | 0.000 |
| CRP0 | 80.05 (27.08, 120.07) | 78.83 (44.42, 121.07) | 0.557 |
| CRP1 | 88.66 (50.59, 138.97) | 76.35 (39.25, 106.63) | 0.245 |
| All results are expressed in the median (interquartile range); HBP – heparin-binding protein; PCT – procalcitonin; CRP – C-reactive protein; HBP0 – HBP measurement at the time of admission; HBP1 – HBP measurement at the first 72 h of admission; PCT0 – PCT measurement at the time of admission; PCT1 – PCT measurement at the first 72 h of admission; CRP0 – CRP measurement at the time of admission; CRP1 – CRP measurement at the first 72 h of admission. | |||