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15 March 2021: Lab/In Vitro Research

Long Noncoding RNA TCONS_00068220 Promotes Breast Cancer Progression by Regulating Epithelial-Mesenchymal Transition Marker E-Cadherin

Xiao Liu 12ABEF , Xingsong Tian 1ACDG

DOI: 10.12659/MSM.929832

Med Sci Monit 2021; 27:e929832

Figure 5 TCONS_00068220 directly interacts with E-cadherin. (A) TCONS_00068220 subcellular localization detected by the nucleus and cytoplasm isolation assay. (B) Biotinylated TCONS_00068220 and its antisense sequence were incubated with MCF-7 and MDA-MB-231cell lysates, respectively, targeted with streptavidin beads, washed, and bound RNAs were subjected to PCR analysis. * P<0.05 vs control.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750