Figure 1 A similar trend of increased mtDNA was also observed in the mitochondria-free cytoplasm of PBMCs from SP patients. (A) Mitochondria-free mtDNA in PBMCs cytoplasm was measured using RT-qPCR targeting the Cytb region of mtDNA. * p<0.05 compared to NSP. (B) Spearman’s rank correlation analyses were performed between PBMCs cytosolic mtDNA and circulating mtDNA in MHD patients. Each dot represents data from one subject.