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20 July 2022: Clinical Research

Bioinformatics Profiling and Experimental Validation of 4 Differentially-Expressed LIM Genes in the Course of Colorectal-Adenoma-Carcinoma

Ying He 12ABEFG , Zongfu Pan 3ACE , Qian Shi 12B , Xilin Zhang 12B , Weiyun Shen 12D , Lixia Huo 12D , Huihui Guo 12D , Chengwu Tang 12FG* , Yuhang Ling 12ACE*

DOI: 10.12659/MSM.937081

Med Sci Monit 2022; 28:e937081

Figure 2 Prognostic significance of the DELGs and their protein expressions in the Human Protein Atlas database. (A) The Kaplan-Meier survival curves of the 4 DELGs in colorectal cancers are depicted. Patients were classified into “High” and “Low” groups based on the gene expression levels, and the median value was chosen as the cut-off. (B) The protein expression and cellular locations of the 4 DELGs were validated by immunohistochemical images from the Human Protein Atlas database (R, version 3.5.1).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750