20 July 2022: Clinical Research
Bioinformatics Profiling and Experimental Validation of 4 Differentially-Expressed LIM Genes in the Course of Colorectal-Adenoma-Carcinoma
Ying He 12ABEFG , Zongfu Pan 3ACE , Qian Shi 12B , Xilin Zhang 12B , Weiyun Shen 12D , Lixia Huo 12D , Huihui Guo 12D , Chengwu Tang 12FG* , Yuhang Ling 12ACE*DOI: 10.12659/MSM.937081
Med Sci Monit 2022; 28:e937081
Figure 4 WGCNA and Module-trait correlation analysis. (A) Sample clustering analysis was performed to exclude outlier samples from GSE117606 and the best β soft threshold was determined depending on scale-free topology and mean connectivity analysis. (B) A hierarchical clustering of the eigengene modules. (C)The adjacency between the eigengene modules is presented in the heatmap. (D) Correlations between the traits (the 4 DELGs, patient age, gender, and pathological subtypes) and the eigengene modules were analyzed and shown in the heatmap (R, version 3.5.1).