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20 July 2022: Clinical Research

Bioinformatics Profiling and Experimental Validation of 4 Differentially-Expressed LIM Genes in the Course of Colorectal-Adenoma-Carcinoma

Ying He 12ABEFG , Zongfu Pan 3ACE , Qian Shi 12B , Xilin Zhang 12B , Weiyun Shen 12D , Lixia Huo 12D , Huihui Guo 12D , Chengwu Tang 12FG* , Yuhang Ling 12ACE*

DOI: 10.12659/MSM.937081

Med Sci Monit 2022; 28:e937081

Figure 7 LMO3 overexpression inhibited colorectal cell proliferation, migration, and invasion. (A) Cell proliferation and migration indices of normal colon epithelial cells (HCoEpiC) and colon cancer cells (HCT116 and RKO) monitored by Real-time Cell Analysis system. For each group, at least 3 biological replicates were included in the analysis. (B) Migrated or invaded cells in Transwell chambers stained by 1% (w/v) crystal violet solution. For each group, at least 3 biological replicates were included in the analysis (Graphpad, version 8.0.2).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750