13 October 2022: Clinical Research
Effects of Hemodilution on Clot Waveform Analysis Parameters, Clotting Factors, and Thrombin Generation Assays in a Dilutional Model Based on Analysis of 11 Healthy Male Blood Donors
Junko Ichikawa ABCDEG* , Ryouta Okazaki BC , Tomoki Fukuda B , Daejoon Yoon B , Makiko Komori DGDOI: 10.12659/MSM.937368
Med Sci Monit 2022; 28:e937368
Figure 2 The effect of isovolemic hemodilution with saline on thrombin generation potentials. Endogenous thrombin potential (ETP) was measured in undiluted and 10–80% diluted plasma from 11 healthy male volunteers. P<0.05 was considered statistically significant with repeated measures two-way analysis of variance. nM – nanomolar; min – minute; ETPp – procoagulant endogenous thrombin potential; ETPi – inhibitory endogenous thrombin potential. * Statistically significant difference from undiluted plasma. Excel (Version 2207, Microsoft) was used for creation of the figure.