13 September 2022: Clinical Research
A Case-Control Study of the Effects of Implementing the Registered Nurses’ Association of Ontario Guidelines for the Assessment and Management of Postoperative Pain and the Use of Relaxation Therapy in 312 Patients with Bone and Soft-Tissue MalignancyQian Gao12ABCDEF, Qi Xu12BC, Xiaowei Zhou12D, Zhaonong Yao12F, Yuhong Yao12AEFG*
Med Sci Monit 2022; 28:e937496
BACKGROUND: The present study aimed to investigate the effects of implementing the Registered Nurses’ Association of Ontario (RNAO) guidelines for the management of postoperative pain and the use of Jacobson’s relaxation technique (JRT) in patients with bone and soft-tissue malignancy at a single center in China.
MATERIAL AND METHODS: A total of 312 patients were recruited and randomly divided into 2 groups. In the intervention group, the RNAO pain-management technique of JRT was adopted, while the control group received the standard institutional nursing management. Pain scores after the operation, according to the Numerical Rating Scale (NRS) combined with the Wong-Baker Faces Pain Rating Scale and Short-Form McGill Pain Questionnaire, were compared between the 2 groups. Nursing satisfaction was compared as well.
RESULTS: At 6, 24, and 72 h after the operation, the NRS scores combined with the Wong-Baker Faces Pain Rating Scale in the intervention group were significantly lower than those in the control group (P<0.001); 72 h after the operation, the Pain Rating Index, Visual Analogue Scale, present pain intensity, and total scores for the intervention group were significantly lower than those for the control group (P<0.001 for all 4 scores). The scores reported from the patients for nursing response and consequent care (P<0.001), nursing competence (P=0.029), and surgical pain-control satisfaction (P<0.001) in the intervention group were also significantly higher than those in the control group.
CONCLUSIONS: JRT can improve postoperative pain-control and nursing satisfaction in patients with malignant bone and soft-tissue tumors. These data suggest a benefit for application of JRT in clinical care.
Keywords: Bone Neoplasms, pain management, Sarcoma
Pain, an unpleasant sensory and emotional experience caused by actual or potential tissue damage, has become the fifth most important vital sign. In the clinical care of patients with bone and soft-tissue malignancy, postoperative pain control is one of the important indicators used to evaluate the quality of nursing care. However, pain control for patients in China is still less than satisfactory, warranting a more standardized and effective pain care management strategy [1,2]. The third edition of the Registered Nurses’ Association of Ontario (RNAO) Best Practice Guideline on the Assessment and Management of Pain (RNAO pain guideline), published in 2013, is designed to apply to all domains of nursing practice, including clinical, administration, and education, to assist nurses in becoming more comfortable, confident, and competent when assessing and managing people with the presence, or risk of, any type of pain. Up to now, there has been no detailed national guideline for pain management for clinical nursing in China. Instead, separate institutional practice guidelines have been used. RNAO pain guidelines have achieved a decrease in the prevalence and intensity of pain in the clinical setting [3,4]. Therefore, it is necessary to explore multimodal analgesia following the RNAO pain guidelines for postoperative pain management in patients with bone and soft-tissue malignancy. In the RNAO guidelines, non-pharmacological regimens are emphasized along with pharmacological approaches. One such technique, non-invasive Jacobson’s relaxation technique (JRT), warrants evaluation in the multimodal analgesia routine.
JRT was originally proposed by Dr. Edmund Jacobson, an American physician, and was originally used to help reduce stress, anxiety, and depression . JRT is a type of physical therapy that includes the sequential tightening and relaxing of specific muscle groups. In further clinical exploration, previous studies have indicated that JRT can help patients with postoperative anxiety relief and pain control [6–8]. JRT emphasizes whole-body progressive muscle relaxation, implying a potentially positive effect on pain control in patients with bone and soft-tissue malignancy, especially those with low pain scores.
The present case-control study aimed to investigate the effects of implementing the RNAO guidelines for the assessment and management of postoperative pain and the use of relaxation therapy in 312 patients with bone and soft-tissue malignancy at a single center in China between January and August, 2021.
Material and Methods
This study was approved by the Ethics Board (IRB) of the Second Affiliated Hospital of Zhejiang University School of Medicine (SAHZU). The original and translated ethics approval documentation was provided to the editor of the journal. This study was conducted in accordance with the principles of the Helsinki Declaration. All of the patients or the guardians of children signed the informed consent before they participated in the study. The participants were fully aware of the procedure of the study.
The study encompassed 312 patients with bone and soft-tissue malignancy undergoing surgery at SAHZU Bone Tumor Center, Department of Orthopaedics from January 2021 to August 2021. The patients were randomly divided into an intervention group and control group with 156 cases in each group. The study participants joined this study according to the following inclusion criteria: clear indications for surgery resulting in surgical treatment, ability to understand and communicate, and reception of patient-controlled analgesia after surgery. However, those who had mental illness or cognitive impairment, experienced severe postoperative complications, dropped out of followup, or could not complete the JRT were excluded from the study.
PAIN EVALUATION METHODS:
Numerical Rating Scale (NRS): patients are asked to circle the number between 0 and 10 that fits best to their pain intensity. Zero usually represents “no pain at all” whereas the upper limit represents “the worst pain ever possible”; 1–3 represents mild pain, 4–6 represents moderate pain, and 7–10 represents severe pain.
Wong-Baker Faces Pain Rating Scale: this scale illustrates face cartoons ranging from a happy face at 0 score, representing “no pain at all”, to a crying face at 10 score, which indicates “the worst pain one can imagine”. According to the face cartoons and written descriptions, the patient chooses the face cartoon that best fits their pain intensity. This method was applied only for patients unable to accomplish the NRS system.
Short-Form McGill Pain Questionnaire (SF-MPQ): The measure is calculated by summing the point values for responses to 15 questions. Questions 1–11 deal with the sensory dimension of pain (Pain Rating Index, PRI). Questions 12–15 deal with the affective dimension of pain. Subscores for the sensory and affective dimensions are calculated, in addition to a total McGill Pain Score. In addition, there is a Visual Analogue Scale (VAS) for pain intensity and a final question about present pain intensity (PPI). Higher scores generally correspond to a worse subjective experience of pain.
Control group: The control group adopted a routine nursing management method described by an institutional guideline in SAHZU. Routine pain assessment and treatment were carried out for postoperative patients according to the “Pain Assessment and Management System” of the authors’ hospital. For patients with a pain score of 1–3, nurses gave psychological support. For patients with a pain score ≥4, timely assessment, instant report to the physician, and pain relief therapeutics would be done according to the physician’s advice. Patients with a pain score ≥7 should be treated as an emergency. Reassessment was required after the pain medicines were taken.
Intervention group: The intervention group adopted the RNAO pain-management protocol of JRT. A multidisciplinary pain-management team was established, including orthopedists, anesthesiologists, and pain-control specialist nurses. Orthopedists are responsible for formulating primary analgesia strategies to alleviate pain based on the results of pain assessment and contacting anesthesiologists for assistance when necessary. Anesthesiologists have key roles in dealing with ineffective postoperative pain control. Pain-control specialist nurses are responsible for the nursing management of pain in patients guided by RNAO pain guidelines, including assessment, planning, implementation, and evaluation. The care plan needs to be comprehensive, and based on the patient’s beliefs, knowledge, and understanding. Pain assessment using multi-dimensional assessment tools: NRS, Wong-Baker Faces Pain Rating Scale for patients with difficulty in expressing their pain using the NRS, and the Short-From McGill Pain Questionnaire. Before surgery, pain-control specialist nurses strengthened pain education and psychological intervention by introducing the causes, influences, and prognosis of the pain, as well as the common postoperative analgesia methods. Misconceptions were also addressed, to ease the concerns of patients and their families about postoperative pain. Multimodal analgesia: in addition to patient-controlled analgesia after surgery, non-pharmacological measures should be taken for patients with NRS scores of 1–3. The nurses should also instruct patients to use JRT combined with psychological support. For patients with NRS score ≥4, the multidisciplinary pain-management team formulated a targeted analgesia plan, with a combination of analgesic drugs and regular re-evaluation of the effectiveness of the pain management.
For JRT, the patient starts from the foot muscle group and moves to the shoulder, continuously contracting and relaxing 16 muscle groups in the body twice a day for 10 min each time. Each muscle group is contracted for 10 s, followed by relaxing the muscle group for 20 s, and consequently moving on to the contraction-relaxation cycle of the next muscle group. Muscle groups that are affected by the surgery or cannot complete this relaxation are skipped, with the patient moving on to the next muscle group.
The effectiveness of pain control of the 2 groups was compared. The NRS combined with the Wong-Baker Faces Pain Rating Scale was used to evaluate the pain intensity on the day of admission and at 6 h, 24 h, and 72 h after the operation. The SF-MPQ was used to evaluate the pain intensity on the day of admission and 72 h after the operation. Satisfaction with the nursing was evaluated using a self-made questionnaire filled out by members of the 2 groups of patients when discharged. The content of the self-made questionnaire included 6 parts: basic information, overall satisfaction with the nursing, satisfaction with nurse-patient communication, satisfaction with nursing response and care, satisfaction with nursing competence, and satisfaction with surgical pain control. The degree of satisfaction was divided into 5 levels: poor (1 point), fair (2 points), good (3 points), very good (4 points), and excellent (5 points).
In this study, Epidata3.1 was used for data input, and SPSS21.0 was used for data analysis. The t-test was used to compare the NRS score, Wong-Baker Faces Pain Rating Scale score, and SF-MPQ score between the intervention group and the control group, as used in Tables 1–3. The t-test was used to compare the satisfaction with nursing care in the 2 groups, as shown in Table 4. P<0.05 was considered statistically significant.
Clinical characteristics of the participants at baseline are shown in Table 1. This study included 312 patients, including 169 male and 143 female patients; the ages ranged from 12 to 75 years old, with an average age of 46.43±20.26 years; among the 312 patients, 213 had primary bone and soft-tissue malignancy, and 99 had metastatic bone and soft-tissue malignancy. The mean age of the intervention group was 46.69±20.58, while the mean age of the control group was 46.17±20.00. There was no statistically significant difference between the 2 groups of patients in terms of sex, age, or tumor type distribution (P>0.05).
As is shown in Table 2, the results of the study showed that there was no statistically significant difference between the 2 groups in NRS scores combined with the Wong-Baker Faces Pain Rating Scale scores on the day of admission. The scores in the intervention group and control group were 5.50±2.13 and 5.63±1.90, respectively (P=0.287). However, 6 h, 24 h, and 72 h after the operation, the NRS combined with the Wong-Baker Faces Pain Rating Scale scores in the intervention group were significantly lower than those in the control group (P<0.001). At the timepoint of 72 h after operation, the scores were 2.76±1.12 in the intervention group, while they were 3.47±1.47 in the control group.
In addition, the PRI, VAS, PPI, and total scores of the SF-MPQ on the day of admission were not statistically different between the intervention group and the control group, with P values of 0.144, 0.287, 0.152, and 0.470, respectively. However, 72 h after the operation, the PRI, VAS, PPI, and total scores of the SF-MPQ were significantly lower than those of the control group (P<0.001 for all of the 4 scores above; Table 3). The SF-MPQ scores in the intervention group 72 h after operation were 5.54±2.86, 2.77±1.13, 1.55±0.98, and 9.87±3.22, whereas they were 7.43±3.56, 3.52±1.45, 2.85±1.17, and 13.78±4.49 in the control group (P<0.001).
The study showed that the patients in the 2 groups were satisfied with the following parameters: “the general nursing during hospitalization”, “the nurses take the initiative to inform regarding relevant matters”, “the nurses respond and help in a timely manner when they encounter problems”, “nurses’ working competence”, and “postoperative pain management and control”, with average scores between “very good” and “excellent”. There was no statistically significant difference between the 2 groups in terms of general nursing (P=0.367) and the level to which the patients felt they were adequately informed about the nursing process (nurse-patient communication) (P=0.112), but the intervention group showed a significantly higher score in nursing response and care (P<0.001), nursing competence (P=0.029), and surgical pain control (P<0.001) (Table 4).
This study had potential limitations. An important limitation of this project was that the effect estimates in this model are based on 312 patients. This sample size is small, and also, the study was performed at only one center. Therefore, a larger sample size and a multiple-center double-blinded controlled trial is needed for future studies. Secondly, we only investigated the short-term results of this model, and we could not draw any conclusions about longer-term effects, which deserve future research through randomized clinical trials.
The RNAO pain guidelines method JRT can improve postoperative pain-control and nursing satisfaction in patients with malignant bone and soft-tissue tumors. It is therefore suggested that this method be widely promoted and applied in clinical nursing. Furthermore, choosing appropriate tools to assess and manage postoperative pain according to the types of diseases and the characteristics of the patients can help patients reduce pain more efficiently.
TablesTable 1. Patient characteristics. There was no statistical difference between the 2 groups regarding sex, age, or tumor types. Table 2. Pain scores (NRS system in combination with Wong-Baker rating scale). Patients in the intervention group had significantly lower scores when compared with individuals in the control group. Table 3. The SF-MPQ scale was used to compare the scores between the intervention group and control group. The scores in the SF-MPQ scale were significantly lower in the intervention group. Table 4. The nursing satisfaction status was compared between the 2 group. The patients in the intervention group had favorable nursing satisfaction in the aspects of nurse-patient communication, nursing responsiveness and care, nursing competence, and pain control.
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