16 June 2004
Value of high resistance index – HRI calculated from Doppler spectrum of popliteal arteries in patients with systemic lupus erythematosus (SLE).
Anna Walecka, Marcin Sawicki, Marek Brzosko, Lidia Ostanek, Katarzyna Fischer, Janusz KordowskiMed Sci Monit 2004; 10(3): 58-62 :: ID: 11871
Abstract
Background:HRI is a new Doppler index of vascular resistance – HRI=D/S.The aim of the study is to evaluate diagnostic significance of HRI calculated from the Doppler spectrum of popliteal arteries in patients with systemic lupus erythematosus (SLE) with and without secondary antiphospholipid syndrome (SAPS) compared with healthy controls.Material/Methods: During 9-month period (May 2003 –January 2004), 93 patients (81 women and 12 men) with SLE (including 24 patients with SAPS) and 30 healthy controls (24 women and 6 men) underwent bilateral duplex Doppler examinations of lower limb arteries. The examinations were performed using HDI 3500 (ATL) with 5 –12 MHz linear transducer under standardized conditions: correct insonation angle and sample volume size, with the patient in a supine position, after 10 minutes rest.Results: Mean HRI value obtained in the control group was 0.415 (range 0.305 –0.555; median 0.402). In the group of SLE patients without SAPS, mean HRI value was decreased to 0.320 (range 0 –0.584;median 0.334) and even lower –0.283 in SLE patients with SAPS (range 0.106 –0.545; median 0.291).Conclusions: Small arteries, arterioles and capillaries are the main affected vessels in SLE. This chronic process stimulates circulation through lower resistance collaterals, decreasing HRI value. The Doppler HRI calculation can be valuable in early diagnosis and monitoring of lower extremity vascular changes in patients suffering from SLE with and without SAPS.
Keywords: Vascular Resistance, Doppler ultrasound, systemic lupus erythematosus, Antiphospholipid Syndrome
Editorial
01 May 2025 : Editorial
Editorial: Surveillance of Seasonal Respiratory Syncytial Virus (RSV) Infection in Children and Vulnerable Adults Drives Vaccine Development and New Immunization ProgramsDOI: 10.12659/MSM.949558
Med Sci Monit 2025; 31:e949558
In Press
Clinical Research
Identifying Risk Factors for Myocardial Injury in Elderly Patients with SepsisMed Sci Monit In Press; DOI: 10.12659/MSM.947840
Laboratory Research
Impact of Margin Type and Material Choice on Stress Distribution in Endocrown Restorations: A 3D Finite Ele...Med Sci Monit In Press; DOI: 10.12659/MSM.948308
Clinical Research
Emergency Department Visits for Pediatric Poisoning in China: A 318-Case ReviewMed Sci Monit In Press; DOI: 10.12659/MSM.946496
Clinical Research
Association of Serum Magnesium and Calcium Levels in Patients with and without Diastolic Notch in Uterine A...Med Sci Monit In Press; DOI: 10.12659/MSM.948411
Most Viewed Current Articles
17 Jan 2024 : Review article 9,024,819
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research 703,237
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Mar 2024 : Editorial 31,016
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and ...DOI :10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
28 Jan 2024 : Review article 24,832
A Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and FutureDOI :10.12659/MSM.943912
Med Sci Monit 2024; 30:e943912