Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

16 June 2004

Bone mineral density and bone metabolism are not related to leptin in hemodialyzed and peritoneally dialyzed uremic patients.

Jolanta Małyszko, Jacek S Małyszko, Zofia Bondyra, Sławomir Wołczyński, Urszula Łebkowska, Michał Myśliwiec

Med Sci Monit 2004; 10(3): 115-119 :: ID: 11880

Abstract

Background:In chronic renal failure leptin levels are elevated and BMD decreased, however, so far data about correlations between leptin and BMD in dialyzed patients are scarce. It has been suggested that leptin is a predictor of BMD in postmenopausal women. We examined the relationships between leptinemia, BMD and bone metabolism in HD and CAPD patients. We also assessed whether leptin is significant and independent predictor of BMD in dialyzed patients.Material/Methods: BMD was measured using dual energy X-ray absorptiometry (DEXA) at lumbar spine and femoral neck in 25 HD and 23 CAPD patients. Markers of bone turnover and leptin were studied using commercially available kits.Results: In femoral neck BMD was significantly higher in CAPD patients, without significant differences in BMD in lumbar spine.There was a negative correlation between BMD at the femoral neck and time on hemodialysis (r=–0.45,p

Keywords: Leptin, hemodialysis, Peritoneal Dialysis, bone mineral density, bone metabolism

Add Comment 0 Comments

Editorial

01 February 2025 : Editorial  

Editorial: Current Approaches to Screening for Lung Cancer in Smokers and Non-Smokers

Dinah V. Parums

DOI: 10.12659/MSM.948255

Med Sci Monit 2025; 31:e948255

0:00

In Press

Clinical Research  

Impact of Osteopathic Techniques on Autonomic Regulation: A Study of Heart Rate Variability in Healthy Adults

Med Sci Monit In Press; DOI: 10.12659/MSM.946903  

0:00

Clinical Research  

Immune Dysregulation in Acute Herpes Zoster: Predictive Factors for Postherpetic Neuralgia

Med Sci Monit In Press; DOI: 10.12659/MSM.944688  

0:00

Clinical Research  

Inflammatory Biomarkers from Blood Counts as Prognostic Tools in Metastatic Esophageal Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.947202  

Laboratory Research  

Comparison of Color Stability Between Single-Shade and Conventional Composite Resins Following Immersion in...

Med Sci Monit In Press; DOI: 10.12659/MSM.946784  

Most Viewed Current Articles

17 Jan 2024 : Review article   6,966,697

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

16 May 2023 : Clinical Research   701,689

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

01 Mar 2024 : Editorial   25,052

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and ...

DOI :10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

28 Jan 2024 : Review article   19,692

A Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and Future

DOI :10.12659/MSM.943912

Med Sci Monit 2024; 30:e943912

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750