01 October 2003
Treatment of blood aspiration syndrome with natural surfactant – does it work in neonates?Ewa Gulczyńska, Agnieszka Zjawiona, Barbara Sobolewska, Marek Nowiczewski, Janusz Gadzinowski
Med Sci Monit 2003; 9(5): 32-35 :: ID: 428687
Background: Exogenous surfactant was introduced into treatment of neonatal RDS over 20 years ago.Since that time indications for surfactant were extended to ‘non-RDS ’aetiology.We present three cases of blood aspiration syndrome treated with exogenous surfactant. Material/Methods: Neonates were delivered by emergency cesarean section at Polish Mother ’s Memorial Hospital beceause of pre- mature placental ablation. Mean gestational age was 37.3 weeks,mean birth weight 2766 g (1700 –3450 g).After tracheal suction- ing under direct laryngoscopy infants were intubated and ventilatory support with high respirator settings was started.Mean initial value of Oxygenation Index (OI)was 36.3 and alveolar-to-arterial oxygen gradient (A-a DO 2 )611.7 torr.All patients were treated with natural surfactant.One infant received two boluses,the remaining two were treated with broncho-alveolar surfactant lavage (5 mg phospholipids/mL;15 mL/kg). Results: In patient who received bolus of surfactant blood clots were obtained from respiratory tract with subsequent improvement of ventilation.In neonates treated with lavage a normalization gas exchange was also noticed (after 24 hours OI dropped by 92.1%and A-a DO 2 by 92.3%).Extubation was possible in all three patients with no signs of pulmonary hemorrhage or other side effects associated with surfactant administration. Conclusions: This first data concerning natural surfactant usage in blood aspiration syndrome suggest potential benefits.
Keywords: blood aspiration syndrome, surfactant, newborn infant
01 March 2023 : EditorialEditorial: Global Surveillance of Highly Pathogenic Avian Influenza Viruses in Poultry, Wild Birds, and Mammals to Prevent a Human Influenza Pandemic
Med Sci Monit 2023; 29:e939968
03 March 2023 : Database AnalysisReinfections from SARS-CoV-2: A Retrospective Study from the Gyncentrum Genetic Laboratory in Sosnowiec, Po...
Med Sci Monit In Press; DOI: 10.12659/MSM.939452
09 February 2023 : Clinical ResearchEvaluation of Health-Related Quality of Life and Mental Health in 729 Medical Students in Indonesia During ...
Med Sci Monit 2023; 29:e938892
19 January 2023 : Clinical ResearchDetermining the Impact of the COVID-19 Pandemic on Dental Care in the Serbian Adult Population: An Online Q...
Med Sci Monit 2023; 29:e939238
27 December 2022 : Clinical ResearchEffect of Physiotherapy to Correct Rounded Shoulder Posture in 30 Patients During the COVID-19 Pandemic in ...
Med Sci Monit 2022; 28:e938926
22 Mar 2023 : Special reportOne Year On: Poland’s Public Health Initiatives and National Response to Millions of Refugees from Ukraine
Med Sci Monit In Press; DOI: 10.12659/MSM.940223
22 Mar 2023 : Clinical ResearchValue of IL-1β and IL-23 in Predicting 28-Day Mortality Due to Sepsis: A Retrospective Study
Med Sci Monit In Press; DOI: 10.12659/MSM.940163
21 Mar 2023 : Clinical ResearchEfficacy of Direct Anterior Approach Versus Posterior Lateral Approach for Total Hip Replacement in Patient...
Med Sci Monit In Press; DOI: 10.12659/MSM.939682
21 Mar 2023 : Clinical ResearchIntraoperative Hypotension and Its Association with Postoperative Acute Kidney Injury in Patients Undergoin...
Med Sci Monit In Press; DOI: 10.12659/MSM.938945
Most Viewed Current Articles
13 Nov 2021 : Clinical ResearchAcceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...
Med Sci Monit 2021; 27:e932788
30 Dec 2021 : Clinical ResearchRetrospective Study of Outcomes and Hospitalization Rates of Patients in Italy with a Confirmed Diagnosis o...
Med Sci Monit 2021; 27:e935379
08 Mar 2022 : Review articleA Review of the Potential Roles of Antioxidant and Anti-Inflammatory Pharmacological Approaches for the Man...
Med Sci Monit 2022; 28:e936292
01 Jan 2022 : EditorialEditorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...
Med Sci Monit 2022; 28:e935952