23 December 2020>: Clinical Research
Safety and Efficacy of Therapeutic Erythrocytapheresis Treatment in Chronic Mountain Sickness Patients in Shigatse, Tibet, China
Mingyuan Niu 1BCD* , Shekhar Singh 2EF* , Ma Mi 1B , Pian Bian 1B , Yawei Xu 2D , Zhuoga Deji 1AB* , Duoji Mima 1A* , Xiankai Li 2ACEG*DOI: 10.12659/MSM.927853
Med Sci Monit 2020; 26:e927853
Table 3 Vital signs and laboratory results of CMS patients before and after TEA treatment.
Before TEA | After TEA | P value | |
---|---|---|---|
SpO (%) | 80.5±5.8 | 93.8±2.6 | |
SBP (mmHg) | 140±19 | 120±12 | |
DBP (mmHg) | 95±14 | 78±14 | |
HR (bpm) | 81±11 | 80±8 | 0.5 |
RBC (×10/L) | 7.48±0.67 | 5.77±0.70 | |
Hb (g/L) | 236±14 | 178±16 | |
Hct (%) | 69.2±4.8 | 53.8±5.6 | |
Platelet (×10/L) | 135±35 | 159±53 | |
ALT (U/L) | 49±31 | 41±20 | >0.05 |
AST (U/L) | 30±11 | 27±6 | >0.05 |
Total protein (g/L) | 72±10 | 65±6 | |
Albumen (g/L) | 44±6 | 41±3 | 0.001 |
Total bilirubin (umol/L) | 36±26 | 21±10 | |
Direct bilirubin (umol/L) | 7±2 | 5±2 | |
Bun (mmol/L) | 4.1±0.9 | 3.8±1.1 | >0.05 |
SCr (umol/L) | 68.9±13.9 | 65.1±14.5 | |
Uric acid (umol/L) | 513.5±124.8 | 387.5±75.5 | |
Blood glucose (mmol/L) | 4.7±1.6 | 4.6±0.8 | >0.05 |
GHbA1C (%) | 6.9±1.3 | 6.5±1.6 | |
TnT (ng/mL) | 0.25±0.05 | 0.25±0.05 | >0.05 |
CK-MB (ng/mL) | 1.58±0.54 | 1.35±0.53 | |
Na (mmol/L) | 141.61±3.23 | 141.32±2.39 | >0.05 |
K (mmol/L) | 3.75±0.56 | 3.89±0.47 | >0.05 |
Cl (mmol/L) | 104.24±2.98 | 105.03±2.20 | >0.05 |
Ca (mmol/L) | 2.33±.015 | 2.28±0.13 | >0.05 |
HPO4 (mmol/L) | 1.00±0.18 | 0.97±0.17 | >0.05 |
TC (mmol/L) | 4.37±0.85 | 3.76±0.64 | 0.001 |
TG (mmol/L) | 1.34±0.56 | 1.15±0.66 | |
LDL-C (mmol/L) | 2.37±0.71 | 1.91±0.50 | 0.001 |
HDL-C (mmol/L) | 1.43±0.31 | 1.35±0.30 | >0.05 |
PT (S) | 13.3±3.8 | 11.4±1.0 | |
APTT (S) | 41.9±18.8 | 30.7±5.0 | |
D-dimer (mg/L) | 0.35±0.25 | 0.35±0.27 | >0.05 |
SBP – systolic blood pressure; DBP – diastolic blood pressure; HR – heart rate; RBC – red blood cell; HB – hemoglobin; Hct – hematocrit; ALT – alanine aminotransferase; AST – aspartate transaminase; BUN – blood urea nitrogen; SCr – serum creatinine; GHbA1c – glycated hemoglobin A1c; TnT – troponin T; CK-MB – creatine kinase-MB; Na – sodium; K – potassium; Cl – chloride; Ca – calcium; HPO4 – phosphorus; TC – total cholesterol; TG – triglycerides; LDL-C – low density lipoprotein cholesterol; HDL-C – high density lipoprotein cholesterol; PT – prothrombin time; APTT – activated partial thromboplastin time. |