24 March 2021>: Clinical Research
Contribution of Interstitial Cells of Cajal to Gastrointestinal Stromal Tumor Risk
Qi Wang 1ABEG* , Zhen-peng Huang 2ACDEF** , Yu Zhu 3B , Fei Fu 1B , Lin Tian 1ABDG*DOI: 10.12659/MSM.929575
Med Sci Monit 2021; 27:e929575
Table 4 ICCs and CD34-positive grade and GISTs risk.
NIH criteria | CD34 (−) | CD34 (+) | CD34 (++) | CD34 (+++) |
---|---|---|---|---|
Very low risk | 4 (9.09%) | 24 (54.54%) | 10 (22.73%) | 6 (13.64%) |
Low risk | 3 (10.35%) | 12 (41.38%) | 10 (34.48%) | 4 (13.79%) |
Intermediate risk | 0 (0.00%) | 6 (37.5%) | 5 (31.25%) | 5 (31.25%) |
High risk | 4 (12.12%) | 9 (27.27%) | 8 (24.25%) | 12 (36.36%) |
# χ=7.8485, =0.0492. Most high-risk GIST cases had very high levels of ICCs and CD34 (+++). Nearly half of the very low-risk and low-risk GIST cases had low levels of ICCs and CD34 (+) (χ=7.8485, =0.0492). |