13 April 2022: Clinical Research
External Quality Assessment of Maternal Serum Levels of Alpha-Fetoprotein, Free Beta-Human Chorionic Gonadotropin, and Unconjugated Estriol in Detecting Down Syndrome and Neural Tube Defects in the Second Trimester of 87 Maternal Serum Samples, Based on 105-139 Days
Yiming Chen 12AEG** , Yijie Chen 2BE* , Yezhen Shi 3CD , Wenwen Ning 2BE , Xiaoying Wang 1B , Liyao Li 1BC , Huimin Zhang 2FDOI: 10.12659/MSM.935573
Med Sci Monit 2022; 28:e935573
Table 5 Comparison of positive rate and detection rate of neural tube defects in 6 different laboratories.
| Laboratory | N | NTD risk value distribution | NTD detection situation | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Low risk | High risk | PR (%) | P value | Low risk | High risk | DR (%) | P value | ||
| Lab A | 83 | 80 | 3 | 3.61 | 0.799 | 2 | 3 | 75.00 | 0.529 |
| Lab B | 83 | 80 | 3 | 3.61 | 2 | 3 | 75.00 | ||
| Lab C | 83 | 82 | 1 | 1.20 | 4 | 1 | 25.00 | ||
| Lab D | 83 | 80 | 3 | 3.61 | 2 | 3 | 75.00 | ||
| Lab E | 83 | 80 | 3 | 3.61 | 2 | 3 | 75.00 | ||
| Lab F | 83 | 82 | 1 | 1.20 | 4 | 1 | 25.00 | ||
| Lab – laboratory; NTD – neural tube defects; PR – positive rate; DR – detection rate. | |||||||||