13 June 2022: Database Analysis
Retrospective Study from a Single Center to Identify Risk Factors Associated with Reinfection in Patients Undergoing 2-Stage Revision Surgery for Periprosthetic Joint Infection
Bingshi Zhang ABCE , Zeming Liu CE , Sikai Liu BC , Bo Liu BC , Mengnan Li B , Wenao Li E , Yongtai Han ABCDE*DOI: 10.12659/MSM.936973
Med Sci Monit 2022; 28:e936973
Table 4 Independent risk factors for infection recurrence in patients with periprosthetic joint infection undergoing 2-stage hip revision surgery.
| Risk factors | HR | 95% CI for the HR | P |
|---|---|---|---|
| CRP | 1.059 | 1.012–1.185 | 0.002 |
| Bacterial infection | |||
| Negative | Ref. | ||
| G+ bacteria | 1.251 | 1.102–1.401 | 0.002 |
| G− bacteria | 2.165 | 1.452–3.022 | 0.032 |
| Age (years) | 1.085 | 1.053–1.201 | |
| Immunosuppression | |||
| No | Ref. | ||
| Yes | 3.208 | 1.121–8.254 | |
| Albumin/globulin | 0.928 | 0.875–0.945 | 0.020 |
| Glucose | 1.095 | 1.008–1.245 | 0.006 |
| MRI findings | |||
| Negative findings | Ref. | ||
| Lamellated hyperintense synovitis or soft tissue edema | 2.336 | 1.569–4.238 | |
| Both | 3.980 | 2.250–6.233 | |
| Ref. – reference; HR – Hazard ratio; CI – confidential interval; CRP – C-reactive protein. Cox proportional hazards regression analysis was used to estimate these HRs, CIs, and P values. All potential risk factors (i.e., all variables reported in and ) were initially included in the regression models. The stepwise regression method was used to determine the final independent variables in the equation. Variables with P>0.1 were removed from the equation. | |||